Palhano Zanela TM, Zangiabadi M, Zhao Y, Underbakke ES. Molecularly imprinted nanoparticles reveal regulatory scaffolding features in Pyk2 tyrosine kinase. RSC Chem. Biol. (2024) 5: 447-453. PMC11078204
Jiang T, Wan G, Zhang H, Gyawali YP, Underbakke ES, Feng C. Probing protein dynamics in neuronal nitric oxide synthase by quantitative cross-linking mass spectrometry. Biochemistry. (2023) 62(15): 2232-2237. PMC10529231
Palhano Zanela TM, Woudenberg A, Romero Bello KG, Underbakke ES. Activation loop phosphorylation tunes conformational dynamics underlying Pyk2 tyrosine kinase activation. Structure (2023) 31(4), 447
Siang S, Underbakke ES, Roche J. Intricate coupling between the transactivation and basic-leucine zipper domains governs phosphorylation of transcription factor ATF4 by casein kinase 2. J. Biol. Chem. (2022) 298(3): 101633. PMC8881488
Agnew C, Ayaz P, Kashima R, Loving HS, Ghatpande P, Kung JE, Underbakke ES, Shan Y, Shaw DE, Hata A, Jura N. Structural basis for ALK2/BMPR2 receptor complex signaling through kinase domain oligomerization. Nat. Commun. (2021) 12, 4950. PMC8368100
Li X, Palhano Zanela TM, Underbakke ES, Zhao Y. Controlling Kinase Activities by Selective Protection of Peptide Substrates, J. Am. Chem. Soc. (2021) 143, 639–643.
Loving HS, Underbakke ES. Conformational dynamics of FERM-mediated autoinhibition in Pyk2 tyrosine kinase. Biochemistry (2019) 58(36): 3767-3776.
Hanson QM, Carley JR, Gilbreath TJ, Smith BC, Underbakke ES. Calmodulin-induced conformational control and allostery underlying neuronal nitric oxide synthase activation. J. Mol. Biol. (2018) 430(7): 935-947
Underbakke ES, Iavarone AT, Chalmers MJ, Pascal BD, Novick S, Griffin PR, Marletta, MA. Nitric oxide-induced conformational changes in soluble guanylate cyclase. Structure (2014) 22(4) 602-11. PMC4001857
Campbell MG, Underbakke ES, Potter CS, Carragher B, Marletta MA. Single particle EM reveals the higher order domain architecture of soluble guanylate cyclase. Proc. Natl. Acad. Sci USA. (2014) 111:2960-65. PMC3939929
Underbakke ES, Surmeli NB, Smith BC, Wynia-Smith SJ, Marletta MA. Nitric oxide signaling. Comprehensive Inorganic Chemistry II, Vol. 3 Oxford: Elsevier (2013) 241-262.
Smith BC, Underbakke ES, Kulp DW, Schief W, Marletta MA. Nitric oxide synthase domain interfaces regulate electron transfer and calmodulin activation. Proc. Natl. Acad. Sci USA. (2013) 110:E3577-86. PMC3780838
Underbakke ES, Iavarone AT, Marletta MA. Higher-order interactions bridge the nitric oxide receptor and catalytic domains of soluble guanylate cyclase. Proc. Natl. Acad. Sci USA. (2013) 110: 6777-82. PMC3637750
Fernhoff NB, Derbyshire ER, Underbakke ES, Marletta MA. Heme-assisted S-nitrosation desensitizes ferric soluble guanylate cyclase (sGC) to nitric oxide. J. Biol. Chem. (2012) 287: 43053-62. PMC3522300
Underbakke ES, Zhu Y, Kiessling LL. Protein footprinting in a complex milieu: identifying the interaction surfaces of the chemotaxis adapter protein CheW. J. Mol. Biol. (2011) 409: 483-495. PMC3179904
Underbakke ES, Zhu Y, Kiessling LL. Isotope-coded Affinity Tags with Tunable Reactivities for Protein Footprinting. Angew. Chem. Int. Ed. (2008) 47: 9677-80. PMC2790078